Effect of Chlorhexidine with Fluoride Mouthrinse on Plaque Accumulation, Plaque pH - A Double Blind Parallel Randomized Clinical Trial

Effect of Chlorhexidine with Fluoride Mouthrinse on Plaque Accumulation, Plaque pH - A Double Blind Parallel Randomized Clinical Trial

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Introduction: Mouthwashes are important means used in chemical control of dental plaque.There is strong evidence suggestive of better effectiveness, when fluoride is added to chlorhexidine mouthwash.Aim: To assess the anti-plaque efficacy of Chlorhexidine combined with Fluoride mouthwash and to measure its impact on plaque accumulation and on plaque pH.Materials and Methods: Initially 100 subjects were screened.

A double blind, parallel randomized clinical trial was conducted on 30 subjects after applying inclusion and exclusion criteria.Other independent variables were matched before randomly allocating them in three groups: Group A-Chlorhexidine as positive control, Group B-Chlorhexidine + fg42 replica Fluoride as test group and Group C- Distilled water as negative control.Oral prophylaxis of participants was done before onset of the study.Plaque pH was assessed before and immediately after rinsing at 0, 5 and 10 minutes interval and after 7 days with digital pH electrode (pHepR pH meter, Hanna Instruments R10285) and accumulation of plaque was recorded by Turesky et al.

, modification of Quigley Hein Plaque Index (1970).ANOVA test was used for statistical analysis.Results: Although there was a statistically significant reduction in mean plaque scores from baseline to seven days sonics empire in both Groups A and B, Group B showed better anti-plaque efficacy.Almost equal drop in plaque pH was seen for both the groups at 5 and 10 minutes.

Conclusion: Better anti-plaque efficacy was observed in Group B (Chlorhexidine and Fluoride combination) with minimum variation of plaque pH.